Research Scientist Engineer 3

Job Description

RESEARCH SCIENTIST ENGINEER 3

Req #: 227558 Department: MEDICINAL CHEMISTRY Job Location: Health Sciences Center, Seattle Campus Posting Date: 10/05/2023 Closing Info: Open Until Filled Salary: $5772 - $5834 per month Other Compensation: Union Position: Yes Shift: First Shift Benefits: As a UW employee, you will enjoy generous benefits and work/life programs. For a complete description of our benefits for this position, please visit our website, click here. As a UW employee, you have a unique opportunity to change lives on our campuses, in our state and around the world. UW employees offer their boundless energy, creative problem solving skills and dedication to build stronger minds and a healthier world.
UW faculty and staff also enjoy outstanding benefits, professional growth opportunities and unique resources in an environment noted for diversity, intellectual excitement, artistic pursuits and natural beauty.
The University of Washington School of Pharmacy is ranked nationally in the top schools of Pharmacy. At the School of Pharmacy, we are committed to educating the next generation of leaders in pharmacy, pharmaceutical research and health care – while seeking to ensure the safe, rational and cost-effective use of medicines.
Medicinal Chemistry has an outstanding opportunity for a Research Scientist Engineer 3.
Duties and Responsibilities: 80%Structural and biophysical characterization of viral proteins and virus particles using structural mass spectrometry. Method development for applying H/D-exchange mass spectrometry to proteins in complex biologically relevant milieu. Data analysis (HDExaminer, DriftScope, Byonic, HX Express, PEAKS, Excel), Cell culture and protein expression and purification (IEX, SEC, Nickel purification), Protein characterization (Native-PAGE, SDS-PAGE, DLS) Buffer and reagent preparation, DNA preparation. 20% Mentor and help train junior researchers in HDX-MS and glycoprofiling methodology as well as sample purification on a limited basis
Minimum Requirements:

Bachelor's Degree in Biochemistry, Chemistry, Biophysics, or equivalent and four years of relevant experience OR Equivalent combination of education/experience.
Equivalent education/experience will substitute for all minimum qualifications except when there are legal requirements, such as a license/certification/registration.
Desired Qualifications:

Doctoral Degree in Biochemistry, Chemistry, Biophysics, or equivalent

Minimum 3 years experience in research lab environment.

Express and purify protein from mammalian and bacteria expression systems.

Carry out H/D-exchange mass spec experiments and analysis.

Perform glycan profiling.

Ability to perform HDX-MS and covalent crosslinking experiments on intact viral particles and virus-like particles
Application Process:
The application process for UW positions may include completion of a variety of online assessments to obtain additional information that will be used in the evaluation process. These assessments may include Workforce Authorization, Cover Letter and/or others. Any assessments that you need to complete will appear on your screen as soon as you select “Apply to this position”. Once you begin an assessment, it must be completed at that time; if you do not complete the assessment you will be prompted to do so the next time you access your “My Jobs” page. If you select to take it later, it will appear on your "My Jobs" page to take when you are ready. Please note that your application will not be reviewed, and you will not be considered for this position until all required assessments have been completed.

Committed to attracting and retaining a diverse staff, the University of Washington will honor your experiences, perspectives and unique identity. Together, our community strives to create and maintain working and learning environments that are inclusive, equitable and welcoming.

The University of Washington is an affirmative action and equal opportunity employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, gender expression, national origin, age, protected veteran or disabled status, or genetic information.

To request disability accommodation in the application process, contact the Disability Services Office at 206-543-6450 or [email protected] .

Applicants considered for this position will be required to disclose if they are the subject of any substantiated findings or current investigations related to sexual misconduct at their current employment and past employment. Disclosure is required under Washington state law .

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