Variant Review Scientist

Job Description

VARIANT REVIEW SCIENTIST

Req #: 224044 Department: LABORATORY MEDICINE AND PATHOLOGY Job Location: UW Medical Center - Montlake Posting Date: 04/19/2024 Closing Info: Open Until Filled Salary: $5,344 - $10,000 per month Other Compensation: Shift: First Shift Benefits:

As an employee you will enjoy generous benefits and work/life programs. For detailed information on Benefits for this position, click here.

The Department of Laboratory Medicine serves as a regional resource for clinical laboratory services required for patient care, research, and educational programs in laboratory medicine. The department now employs 1400 people who work at the award-winning University of Washington Medical Center (ranked among the top medical centers in the United States as rated by U.S. News & World Report), Harborview Medical Center (the region's only Level I Trauma center, known for innovations and excellence in trauma care and its centers of emphasis: Trauma, Burn, Neurosciences, AIDS/STD CARER, and mentally- and medically- vulnerable populations.), and many other clinical and research facilities in the area. The University of Washington (UW) is proud to be one of the nation’s premier educational and research institutions. Our people are the most important asset in our pursuit of achieving excellence in education, research, and community service. Our staff not only enjoys outstanding benefits and professional growth opportunities, but also an environment noted for diversity, community involvement, intellectual excitement, and natural beauty.
The Department of Laboratory Medicine and Pathology department has an outstanding opportunity for a VARIANT REVIEW SCIENTIST (FULL-TIME, DAY-SHIFT) . This position’s location is hybrid; work location is part work from home and part on-site work at UW Montlake.
RESPONSIBILITIES:
Data Analysis

Generates data and responsible for review and interpretation of genomic test results under direction of clinical laboratory directors.

Provide analysis and consultant to physicians and scientists in other departments as needed to guide development, implementation and interpretation of genomic test services.

Review patient medical history to determine eligibility for exome NGS testing.

Write patient reports for review by genetics, neurology, and other healthcare specialty clients.

Interpret data from high complexity genomic techniques including next generation sequencing and arrays.

Develop and coordinate data analysis strategies and implementation for large research projects

Develop relationships and independently consult experts in the field to assist with interpretation of challenging variants
Development and Maintenance

Responsible to review genomic data and maintain the active knowledgebase for variant interpretation.

Update variant curation strategies, variant scoring process, interpretation process, and reporting process on an ongoing basis.

Develop expertise in interpreting genetic data from open source and proprietary analysis softwares and databases.

Design of tools to assist in more efficient variant review for the variant review scientist and affiliated faculty
Scholarly activities

Responsible for extensive literature review and provide consult, input and collaborates in interdepartmental journal clubs for ongoing education.

Responsible to generate, develop, and provide data at client meetings and conferences, when required.
REQUIREMENTS:

Master’s Degree in genetics, genomics, molecular biology, chemistry, biochemistry or related discipline and two to three years of experience.

Equivalent experience substitute for degree requirement

Experience with next-generation sequencing methods and data analysis.

Experience in genetic variant interpretation for oncology-based and/or exome NGS tests.

Experience in molecular biology methods and data analysis.

Strong teamwork, interpersonal, and managerial skills.

Strong organizational and documentation skills suitable to a clinical laboratory environment.

Demonstrated ability to rapidly distill concise and succinct summaries from complex and potentially contradictory literature sources.

Must be comfortable using a variety of computational databases to aid in the interpretation of genomic variants.

Previous experience working in a diagnostic laboratory desired, with experience reviewing medical literature and pathology reports a plus.

Ability to work independently.

Ability to prioritize and work under tight deadlines.

Excellent verbal and written communication and organizational skills.
DESIRED REQUIREMENTS:

Ph.D. in genetics, genomics, molecular biology, chemistry, biochemistry or related discipline.

Committed to attracting and retaining a diverse staff, the University of Washington will honor your experiences, perspectives and unique identity. Together, our community strives to create and maintain working and learning environments that are inclusive, equitable and welcoming.

The University of Washington is an affirmative action and equal opportunity employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, gender expression, national origin, age, protected veteran or disabled status, or genetic information.

To request disability accommodation in the application process, contact the Disability Services Office at 206-543-6450 or [email protected] .

Applicants considered for this position will be required to disclose if they are the subject of any substantiated findings or current investigations related to sexual misconduct at their current employment and past employment. Disclosure is required under Washington state law .

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