Scientist I - Medicinal Chemistry

Job Description

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Job Description

About the role:

Are you looking for a patient-focused, innovation-driven company that will inspire you and empower you to shine? Join us as a Scientist I in our San Diego laboratories.

Takeda, we are transforming the pharmaceutical industry through our R&D-driven market leadership and being a values-led company. To do this, we empower our people to realize their potential through life-changing work. Certified as a Global Top Employer, we offer stimulating careers, encourage innovation, and strive for excellence in everything we do. We foster an inclusive, collaborative workplace, in which our global teams are united by an unwavering commitment to deliver Better Health and a Brighter Future to people around the world.

As a Scientist I in the GI Chemistry group, you will be a vital contributor to our mission to discover and develop medicines for patients.

OBJECTIVES/PURPOSE

• Takeda seeks a creative and highly motivated scientist to enhance our ability to discover medicines. The successful candidate will apply innovative synthetic organic and medicinal chemistry principles to design, synthesize, and characterize novel, functional molecules within a drug discovery setting that leverages a variety of therapeutic modalities.
• Opportunity to develop skills and knowledge in a cutting-edge, modality agnostic drug discovery unit to create products to serve patients with gastrointestinal and liver disease.
• Strong laboratory-based focus, experimental excellence, and well-developed communication and collaboration skills are required for this position

How you will contribute:

ACCOUNTABILITIES

• Design, synthesize, and characterize bioactive target molecules to address issues of potency and drug-like properties
• Develop innovative and efficient synthetic routes
• Act as a key member of a multidisciplinary drug discovery project team, assist with development of project strategy, coordination of research activities, and analysis and communication of complex data
• Contribute to ongoing innovation within medicinal chemistry through familiarity with recent methods in synthetic organic chemistry
• Maintain a broad current understanding of the scientific and technological landscapes of organic synthesis, medicinal chemistry, and drug discovery, as well as the scientific literature related to a specific drug discovery project
• Keep an accurate, comprehensive, concise notebook in accordance with company policy
• Identify routine obstacles to progress; solve a variety of problems
• Prepare and present research to range of internal and external audiences, through presentations, posters, and contributions to authorship of patents and scientific manuscripts

DIMENSIONS AND ASPECTS

• Diverse practical experience in synthetic organic chemistry
• Demonstrated clear understanding of experimental design and reaction mechanism
• Good understanding of basic biochemical and biological principles
• High level of expertise in modern laboratory and analytical methods
• Proficiency with basic chemistry and laboratory research software required
• Experience with molecular modeling and/or structure-based design tools are a plus
• Recognizes problems and considers the significance of irregularities

Minimum Requirements/Qualifications:

• PhD degree in a scientific discipline (or equivalent), or
• M.S. in Chemistry with 6+ years of relevant chemistry research experience, or
• B.S. with 8+ years of relevant chemistry research experience
• Scientific expertise in organic chemistry, strong knowledge of modern organic chemistry literature, in-depth knowledge of commonly used purification and spectroscopic characterization techniques
• Outstanding oral and written communication skills and the ability to present rationale, key data, issues, and accomplishments to project teams
• Strong collaboration skills, with the ability to work effectively within a diverse team
• A high level of creativity and productivity with respect to laboratory contribution, with strong problem-solving skills directed toward achievement of project milestones
• Internally motivated to learn and develop within role

What Takeda can offer you:

• Comprehensive Healthcare: Medical, Dental, and Vision
• Financial Planning & Stability: 401(k) with company match and Annual Retirement Contribution Plan
• Health & Wellness programs including onsite flu shots and health screenings
• Generous time off for vacation and the option to purchase additional vacation days
• Community Outreach Programs and company match of charitable contributions
• Family Planning Support
• Flexible Work Paths
• Tuition reimbursement

More about us:

At Takeda, we are transforming patient care through the development of novel specialty pharmaceuticals and best in class patient support programs. Takeda is a patient-focused company that will inspire and empower you to grow through life-changing work.

Certified as a Global Top Employer, Takeda offers stimulating careers, encourages innovation, and strives for excellence in everything we do. We foster an inclusive, collaborative workplace, in which our teams are united by an unwavering commitment to deliver Better Health and a Brighter Future to people around the world.

In accordance with the CO Equal Pay Act, Colorado Applicants Are Not Permitted to Apply.

EEO Statement

Takeda is proud in its commitment to creating a diverse workforce and providing equal employment opportunities to all employees and applicants for employment without regard to race, color, religion, sex, sexual orientation, gender identity, gender expression, parental status, national origin, age, disability, citizenship status, genetic information or characteristics, marital status, status as a Vietnam era veteran, special disabled veteran, or other protected veteran in accordance with applicable federal, state and local laws, and any other characteristic protected by law.

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