Associate Scientist

Job Description

Req #: 1903625
Location: Munich, Bavaria, Germany
Job Category: Technical Development
Work Location: Grillparzerstrasse 10-18 81675
Organization: Bioengineering
Employee Status: Full-time
Job Type: Regular

Juno Therapeutics GmbH Munich (a Celgene owned company) is seeking an Associate Scientist to support the development of allogenic engineered T-cell products. The team is responsible for advanced manufacturing solutions that support the development of gene-engineered T cell therapies. Successful candidates will have a strong foundation in human T cell biology and a proven track-record of implementation and optimization of a broad range of in vitro cell-based and molecular assays using human immune and tumor cells. The ability to work in cross-functional teams and yet having a high degree of independence is required.
PRIMARY RESPONSIBILITIES

• Develop and implement strategies for producing and controlling gene-engineered T cells at various stages of the manufacturing process.
• Develop methodologies to purify/refine gene-engineered T cells.
• Maintain critical quality attributes of gene-engineered T cells.
• Serve as T cell biology subject matter expert in a multidisciplinary team setting that includes non-clinical, clinical, translational, discovery, regulatory, and CMC functions.

BASIC QUALIFICATIONS
• Ph.D. degree in immunology or related field.
• 4+ years of experience in the field of human immunology.
• Expertise in multi-parameter flow cytometry and in vitro T cell functional assays.
• Demonstrated independence in experimental design, data analysis, interpretation, and presentation.
• Willingness to learn new cutting-edge methodologies.
• Willingness to contribute to development of novel manufacturing technologies.
• Experienced in using MS Office (required), GraphPad Prism and FlowJo (beneficial) programs.
• Excellent communication and writing skills in English (required) and German (beneficial).
PREFERRED QUALIFICATIONS
• Experience with gene-engineering of T cells using viral or non-viral modalities.
• Experience with statistical analysis, DoE and data visualization software packages (JMP).
• Experience with multi-attribute molecular platforms for characterizing immune cells.
• Experience with T cell manufacturing process.
About Us
COMMITTED TO IMPROVING THE LIVES OF PATIENTS WORLDWIDE
At Celgene, we seek to deliver truly innovative and life-changing drugs for our patients. Our vision as a company is to build a major global biopharmaceutical corporation while focusing on the discovery, the development, and the commercialization of products for the treatment of cancer and other severe, immune, inflammatory conditions.
"At Celgene, we seek to deliver truly innovative and life-changing drugs for our patients."
There are more than 300 clinical trials at major medical centers using compounds from Celgene. Investigational compounds are being studied for patients with incurable hematological and solid tumor cancers, including multiple myeloma, myelodysplastic syndromes, chronic lymphocytic leukemia (CLL), non-Hodgkin’s lymphoma (NHL), triple-negative breast cancer and pancreatic cancer. As committed as we are to clinical accomplishment, we are equally committed to patient support, which is a guiding principle at Celgene. We believe all who can benefit from our discoveries should have the opportunity to do so. Celgene puts patients first with industry-leading programs that provide information, support and access to our innovative therapies.