Job Description

Research Scientist I

Job ID 2024-53109 Area of Interest Research & Development Location Name 1920 Terry FTE/Hours per pay period 1.0 FTE (80 hours per bi-weekly pay periods) Work Status Regular Department B Towne Ctr Chldhd Cancer Rsch Shift Day Shift Primary Location : City Seattle Primary Location : State/Province WA Hot Job No

Responsibilities

The Rau lab is a translational leukemia lab with expertise in the biology of hematologic malignancies. The focus of the lab is the genomic and epigenetics of leukemogenesis and chemoresistance. The lab’s recent work includes a translational study defining the histone modifier, DOT1L as a novel epigenetic target for the treatment of acute myeloid leukemia (AML) with mutations of the gene DNMT3A , defining the SWI/SNF complex as a targetable vulnerability in pediatric AML, use of CRISPR/Cas9 to model genetic lesions leading to chemotherapy resistance in human leukemia and multiple projects examining the interaction of co-occurring mutations in murine models of leukemia. For this work we use a variety of lab techniques including mouse modeling, genome engineering, in vitro and in vivo drug testing and next generation sequencing to study the genetic, transcriptomic and epigenetic underpinnings of hematology malignancies.

This is a unique type of position that requires significant individual initiative and motivation to learn and understand both existing and new scientific methods and knowledge. The Research Scientist will be given the opportunity and be responsible for conducting independent and creative research related to the overall mission of the laboratory. This is an ideal position for those considering graduate school in a related field or medical school in the near future (up to two years). Overall responsibilities include acquiring an in-depth understanding of the field in which they are working, and working with the PI, as well as independently, on the planning, design, execution, trouble-shooting, and interpretation of experiments; makes detailed observations, records data and presents results; assists post docs and fellows in the day-to-day activities and interprets experiments related to assigned projects. The Research Scientist will spend the majority of their time making contributions to on-going laboratory projects, requiring the ability to use independent judgment to address tasks and projects, and will identify and refine existing procedures and practices. The incumbent may also participate in the management of a small rodent colony.

Requirements

Required Education/Experience:

• Bachelor’s Degree in biology, microbiology, immunology, molecular biology or biochemistry.
• Prior experience in a laboratory setting.

Required Credentials:

• N/A.

Preferred:

• Research experience in biochemistry, molecular biology, and tissue culture techniques is highly preferred.

Min to Max Hourly Salary

$25.09 - $37.64 /hr

Min to Max Annual Salary

$52,187.20 - $78,291.20 /yr

Salary Information

This compensation range was calculated based on full-time employment (2080 hours worked per calendar year). Offers are determined by multiple factors including equity, skills, experience, and expertise, and may vary within the range provided.

Disclaimer for Out of State Applicants

This compensation range is specific to Seattle, positions located outside of Seattle may be compensated differently depending on various factors .

Benefits Information

Seattle Children’s offers a generous benefit package, including medical, dental, and vision plans, 403(b), life insurance, paid time off, tuition reimbursement, and more. Click here for more information.

About Us

Hope. Care. Cure. These three simple words capture what we do at Seattle Children’s – to help every child live the healthiest and most fulfilling life possible. Are you ready to engage with a mission-driven organization that is life-changing to many, and touches the hearts of all? #HOPECARECURE

As one of the nation's top five pediatric research centers, Seattle Children's Research Institute is dedicated to providing hope, care, and cures to help every child live the healthiest and most fulfilling life possible.

Our investigators are involved in hundreds of projects that cover every phase of research, from studying how diseases work to improving investigational therapies. They have pioneered groundbreaking cystic fibrosis treatments and cutting-edge cancer therapies that help a child's immune system defeat cancer, and made other major contributions to pediatric medicine.

Researchers work in close collaboration with one another, their colleagues at partner institutions including the University of Washington and Fred Hutch and our healthcare providers at Seattle Children's Hospital, one of U.S. News & World Report’s top children's hospitals. This collaboration is one of our key strengths, allowing our faculty to draw on a variety of disciplines and techniques as they pursue solutions to some of medicine's most complex problems.

We are committed to not only treating disease but to eliminating it. Help us achieve our vision of being a worldwide leader in pediatric research aimed to improve the health and well-being of children. If you are interested in a challenging career aimed at groundbreaking research, Seattle Children's Research Institute is the place for you.

Our Commitment to Diversity

Our community welcomes diverse experiences, backgrounds, and thoughts as this is what drives our spirit of inquiry and allows us to better connect with our increasingly diverse patients and families. Our organization recruits, employs, trains, compensates, and promotes without regard to race, religion, color, national origin, gender (including pregnancy, childbirth, or related medical conditions), sexual orientation, gender identity, gender expression, age, status as a protected veteran, status as an individual with a disability, or other applicable legally protected characteristics.

The people who work at Seattle Children’s are members of a community that seeks to respect and celebrate all the qualities that make each of us unique. Each of us is empowered to be ourselves within this community, which cultivates and promotes equity, diversity, and inclusion at all levels.

Seattle Children’s is proud to be an Equal Opportunity Workplace and Affirmative Action Employer.

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